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    Anastrozole
Anastrozole tablet Anastrozole review
by
Pharmacy and Drugs


     .: Prescription

Anastrozole is used to treat certain types of breast cancer by blocking the use of estrogen that is required by the cancer to grow. It is indicated for treatment of advanced breast cancer in post-menopausal women whose disease progressed following treatment with tamoxifen or other anti-estrogens.

Special precautions: before taking anastrozole, tell your doctor if you have any other medical conditions such as moderate to severe renal impairment or if you take other medications. You may not be able to take anastrozole, or you may require a dosage adjustment or special monitoring during treatment.

Anastrozole is in the FDA pregnancy category D. This means that anastrozole is known to harm an unborn baby. Do not take anastrozole if you are pregnant. It is not known whether anastrozole passes into breast milk. Do not take anastrozole if you are breast-feeding a baby.

There are no restrictions on food, beverages, or activities while taking anastrozole. Take anastrozole exactly as directed by your doctor. It is usually taken once a day and can be taken with or without food. If you missed a dose, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless your doctor directs otherwise.

An overdose of anastrozole is unlikely to threaten life. Nevertheless, seek emergency consult if you suspect that a very large dose of anastrozole has been ingested.

Stop taking anastrozole and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives). Other less serious side effects may be more likely to occur. Continue to take anastrozole and talk to your doctor if you experience the following symptoms: diarrhea; nausea or vomiting; constipation; weakness; muscle or bone pain; headache; hot flashes; shortness of breath or coughing; dizziness; swelling or water retention; loss of appetite; vaginal dryness; weight gain; or rash. Side effects other than those listed here may also occur. Talk to your doctor about any other side effect that seems unusual or that is especially bothersome.

There are no known interactions between anastrozole and other medications. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines during treatment with anastrozole.

ARIMIDEX (anastrozole) tablets for oral administration contain 1 mg of anastrozole, a non-steroidal aromatase inhibitor. It is chemically described as 1,3-Benzenediacetonitrile, a, a, a’, a’-tetramethyl-5- (1H-1,2,4-triazol-1-ylmethyl). Its molecular formula isC17H19N5. Anastrozole is an off-white powder with a molecular weight of 293.4. Anastrozole has moderate aqueous solubility (0.5 mg/mL at 25C); solubility is independent of pH in the physiological range. Anastrozole is freely soluble in methanol, acetone, ethanol, and tetrahydrofuran, and very soluble in acetonitrile. Each tablet contains as inactive ingredients: lactose, magnesium stearate, hydroxypropylmethylcellulose, polyethylene glycol, povidone, sodium starch glycolate, and titanium dioxide.

Anastrozole has the following structural formula:

Chemical structure of Anastrozole
Brand name: Arimidex

Similar drugs: Letrozole :: Tamoxifen Citrate :: Climara

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