Anafranil belongs to the family of tricyclic antidepressants and is most commonly used to treat the symptoms of obsessive-compulsive disorders. Generically prescribed as clomipramine, it is also used to treat symptoms related to panic attacks, arm burning and hair pulling and other body abusive disorders, narcoleptic pain, premenstrual syndrome, and phobias.
It is not uncommon for patients to experience suicidal thoughts when first starting Anafranil. While it is vital to avoid alcohol to help minimize these thoughts and behaviors, it is also important to avoid alcohol to avoid the risk of potential seizures.
Anafranil should be taken with food in order to prevent an upset stomach. A patient that is scheduled for a surgical procedure may very well have to come off the medication prior to surgery. Prolonged exposure to the sun may result in severe sunburns, as tricyclic antidepressants increase sensitivity to sunlight and temperature.
There are basic risks that coincide with a medication like Anafranil. It is absolutely vital that a minimum of five weeks has gone by if a patient has been taking an MAO inhibitor or and ACE inhibitor or most types of anti-psychotic medications. Any previous medication associated with mental health may result in a fatal interaction with Anafranil.
Other patients that have certain health issues should not be prescribed this or any other tricyclic antidepressant. Patients with seizure or heart impairment histories, those with a kidney or liver disease, patients who have been diagnosed with bi-polar disorder, and those with glaucoma or difficulty urinating should not use Anafranil.
Overdoses of Anafranil are not only fatal nearly 100% of the time, but they lead to a violent death for the patient. Extreme heart rates and drowsiness is followed by confusion and agitation. Vomiting, blurry vision, and profuse sweating and swelling set in within minutes. Muscle stiffness and difficulty breathing make the patient very uncomfortable, and the blue tint to their fingers and lips are a sign that oxygen is not getting through the body adequately. A coma mercifully sets in shortly after the convulsions begin, and almost always, the final stage is death.
Severe side effects when the medication is taken normally can result in death as well and it is vital that the patient report these symptoms to their physician immediately. Symptoms such as chest pain that spreads down the arm or sudden numbness or weakness that monopolizes one side of the body are signs of heart attacks and strokes. Sudden onset headaches and confusion and a lack of coordination may also be a sign of a stroke. Fainting, pale skin, easy bruising or bleeding, and frequent urination are all serious side effects that require medical attention. The patient should seek immediate medical attention if they experience a fever accompanied with accelerated heart rate, confusion, sweating, and muscle stiffness.
Less serious side effects that can typically be tolerated include nausea, vomiting, and constipation or diarrhea. Dry mouth with an altered taste is common, as is appetite and weight fluctuations. Sleep problems with vivid night terrors occur in about 20% of patients. Sweating, blurry vision, and sexual dysfunction are fairly typical.
The list of dangerously interactive medication is very long and prior to starting any medication, the patient should seek their physician’s advice. Heart and blood pressure medications, anti psychotics, blood thinners, hormones, seizure medications, cold and allergy drugs, Tagamet, phenytoin, and every psychotropic medication are one the list.
For those patients who can withstand the side effects and exercise caution when utilizing other medications, Anafranil can significantly reduce symptoms and return patients to a reasonable quality of life.
Anafranil (clomipramine hydrochloride capsules, USP), is an antiobsessional drug that belongs to the class (dibenzazepine) of pharmacologic agents known as tricyclic antidepressants. Anafranil is available as capsules of 25, 50, and 75 mg for oral administration. Clomipramine hydrochloride is 3-chloro-5- [3-(dimethylamino)propyl] -10,11-dihydro-5H-dibenz [b,f]azepine monohydrochloride. Clomipramine hydrochloride is a white to off-white crystalline powder. It is freely soluble in water, in methanol, and in methylene chloride, and insoluble in ethyl ether and in hexane.
Anafranil has the following structural formula: