Ampicillin
This page contains drug information aimed
at the consumer and includes the following:
- what is ampicillin
- what are the possible side effects
- what happens if you miss a dose
- what happens if you overdose
- the most important information about ampicillin
- how to use this drug
- other drugs that may affect ampicillin
- what to avoid while using this drug
|
|
Generic Name: ampicillin (am pi SILL in)
Brand Names:
Omnipen, Principen, Totacillin |
|
What is the most important information I should know about
ampicillin?
|
|
• |
Take all of the ampicillin that has been prescribed for you
even if you begin to feel better. Your symptoms may begin to improve
before the infection is completely treated. |
|
• |
Do not break, chew, open, or crush the capsules. Swallow
them whole. |
|
• |
Ampicillin may decrease the effectiveness of birth control
pills. Use a second method of birth control while taking ampicillin to
protect against pregnancy. |
|
• |
Ampicillin is an antibiotic in the class of drugs called
penicillins. Ampicillin fights bacteria in your body. |
|
• |
Ampicillin is used to treat many different types of
infections, such as tonsillitis, pneumonia, bronchitis, urinary tract
infections, gonorrhea, and infections of the intestines such as
salmonella (food poisoning). |
|
• |
Ampicillin may also be used for purposes other than those
listed in this medication guide. |
|
Who should not take ampicillin?
|
|
• |
If you have ever had an allergic reaction to another
penicillin or to a cephalosporin, do not take ampicillin unless your
doctor is aware of your allergy and monitors your therapy. |
|
• |
Before taking this medication, tell your doctor if you have
kidney disease, stomach or intestinal disease, or infectious
mononucleosis. You may not be able to take ampicillin because of an
increased risk of side effects. |
|
• |
If you are a diabetic, some glucose urine tests may give
false positive results while you are taking ampicillin. |
|
• |
Ampicillin is in the FDA pregnancy category B. This means
that it is unlikely to harm an unborn baby. Ampicillin is generally
considered to be safe for use during pregnancy. Do not, however, take
this medication without first talking to your doctor if you are pregnant. |
|
• |
Ampicillin passes into breast milk. Rarely, ampicillin may
cause a yeast infection, diarrhea, or allergic reaction in a nursing
infant, although no serious harm is expected. Do not take this
medication without first talking to your doctor if you are
breast-feeding a baby. |
|
How should I take ampicillin?
|
|
• |
Take ampicillin exactly as directed by your doctor. If you
do not understand the instructions, ask your nurse, doctor, or
pharmacist to explain them to you. |
|
• |
Take each dose with a full glass of water. |
|
• |
Take ampicillin on an empty stomach 1 hour before or 2 hours
after meals. |
|
• |
Ampicillin should be taken at evenly spaced intervals
throughout the day and night to keep the level in your blood high enough
to treat the infection. |
|
• |
Do not crush, chew, or open the ampicillin capsules. Swallow
them whole. |
|
• |
Shake the liquid form of ampicillin well before measuring a
dose. To ensure that you get a correct dose, measure the suspension with
a dose-measuring spoon or cup, not a regular tablespoon. If you do not
have a dose-measuring device, ask your pharmacist where you can get one. |
|
• |
Take all of the ampicillin that has been prescribed for you
even if you begin to feel better. Your symptoms may start to improve
before the infection is completely treated. |
|
• |
Store the tablets and capsules at room temperature and store
the suspension in the refrigerator for longer use. The suspension is
good for 7 days at room temperature and for 14 days if it is stored in
the refrigerator. Throw away any unused liquid after this amount of
time. |
|
What happens if I miss a dose?
|
|
• |
Take the missed dose as soon as you remember. However, if it
is almost time for your next dose, skip the dose you missed and take
only your next regularly scheduled dose. Do not take a double dose of
this medication unless otherwise directed by your doctor. |
|
• |
If you have only missed one dose, you can take the rest of
your scheduled doses for the day at evenly spaced intervals. |
|
What happens if I overdose?
|
|
• |
Seek emergency medical attention. |
|
• |
Symptoms of an ampicillin overdose include muscle spasms or
weakness, pain or twitching, pain in the fingers or toes, loss of
feeling in the fingers or toes, seizures, confusion, coma, and agitation. |
|
What should I avoid while taking ampicillin?
|
|
• |
Alcohol may irritate your stomach if taken with ampicillin,
so use it with moderation. |
|
What are the possible side effects of ampicillin?
|
|
• |
If you experience any of the following serious side effects,
stop taking ampicillin and seek emergency medical attention: |
| |
· |
an allergic reaction (shortness of breath; closing of your
throat; hives; swelling of your lips, face, or tongue; rash; or fainting); |
| |
· |
severe watery diarrhea and abdominal cramps; or |
| |
· |
unusual bleeding or bruising. |
|
• |
Other, less serious side effects may be more likely to occur.
Continue to take ampicillin and talk to your doctor if you experience |
| |
· |
mild nausea, vomiting, diarrhea, or abdominal pain; |
| |
· |
white patches on the tongue (thrush/ yeast infection); |
| |
· |
itching or discharge of the vagina (vaginal yeast infection);
or |
| |
· |
black, "hairy" tongue or sore mouth or tongue. |
|
• |
Side effects other than those listed here may also occur.
Talk to your doctor about any side effect that seems unusual or that is
especially bothersome. |
|
What other drugs will affect ampicillin?
|
|
• |
Some drugs may decrease the effects of ampicillin and
prevent it from properly treating your infection. Before taking
ampicillin, tell your doctor if you are taking any of the following
drugs: |
| |
· |
cholestyramine (Questran) or colestipol (Colestid); or |
| |
· |
another antibiotic (for the same or for a different
infection) such as erythromycin (Ery-Tab, E-Mycin, E.E.S., others),
tetracycline (Sumycin, others), minocycline (Minocin), doxycycline (Doryx,
Vibramycin, others), or any other. |
|
• |
Ampicillin may decrease the effectiveness of birth control
pills. Use a second method of birth control while taking ampicillin to
protect against pregnancy. |
|
• |
Ampicillin increases the effects of methotrexate, and you
may need a dose adjustment during therapy with ampicillin. |
|
• |
Ampicillin also increases the side effects of allopurinol (Zyloprim)
and may cause a rash. |
|
• |
Probenecid (Benemid) increases the effects of ampicillin.
These drugs may be used together for this purpose; however, be sure your
doctor is aware if you are taking probenecid. You may need a lower dose
of ampicillin. |
|
• |
Drugs other than those listed here may also interact with
ampicillin. Talk to your doctor and pharmacist before taking any
prescription or over-the-counter medicines. |
|
Where can I get more information?
|
|
• |
Your pharmacist has additional information about ampicillin
written for health professionals that you may read. |
|
• |
Remember, keep this and all other medicines out of the reach
of children, never share your medicines with others, and use this
medication only for the indication prescribed. |
|
• |
Every effort has been made to ensure that the information
provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and
complete, but no guarantee is made to that effect. Drug information
contained herein may be time sensitive. Multum information has been
compiled for use by healthcare practitioners and consumers in the United
States and therefore Multum does not warrant that uses outside of the
United States are appropriate, unless specifically indicated otherwise.
Multum's drug information does not endorse drugs, diagnose patients or
recommend therapy. Multum's drug information is an informational
resource designed to assist licensed healthcare practitioners in caring
for their patients and/ or to serve consumers viewing this service as a
supplement to, and not a substitute for, the expertise, skill, knowledge
and judgment of healthcare practitioners. The absence of a warning for a
given drug or drug combination in no way should be construed to indicate
that the drug or drug combination is safe, effective or appropriate for
any given patient. Multum does not assume any responsibility for any
aspect of healthcare administered with the aid of information Multum
provides. The information contained herein is not intended to cover all
possible uses, directions, precautions, warnings, drug interactions,
allergic reactions, or adverse effects. If you have questions about the
drugs you are taking, check with your doctor, nurse or pharmacist. |
Copyright 1996-2004 Cerner Multum, Inc. Version: 3.04. Revision
Date: 1/ 23/ 04. |
|