Alimta, known also as Pemetrexed, belongs to the group of medicines called antineoplastics. It is used to treat a type of cancer called malignant pleural mesothelioma (MPM), that affects the inside lining of the chest cavity. Alimta is also used to treat a type of lung cancer.
Be sure to tell your doctor of any allergies you have whether it is to medication or food, preservatives, or dyes. Tell your doctor immediately if you are, or become pregnant, or are breastfeeding, as Alimta has been shown to affect unborn babies. Also, tell your doctor of any other medications you are taking, including vitamins and supplements, and any medical conditions you may have.
It is very important that you take this medicine exactly as your doctor tells you to. Do not take more or less medicine than directed, and never stop taking Alimta without discussing it with your doctor first.
If you miss a dose of this medicine, take it as soon as you remember, unless it is almost time for your next dose. Do NOT double doses.
Check with your doctor immediately if any of the following side effects occur: black, tarry stools; bleeding gums; chest pain; chills; cough; fever; loss of coordination; lower back or side pain; pains in chest, groin, or legs, especially calves of legs; painful or difficult urination; pale skin; pinpoint red spots on skin; severe headaches of sudden onset sudden; shortness of breath; sore throat; sudden onset of slurred speech; sudden vision changes; swollen glands; troubled breathing; ulcers, sores, or white spots in mouth; unusual bleeding or bruising; or unusual tiredness or weakness.
ALIMTA®, pemetrexed for injection, is an antifolate antineoplastic agent that exerts its action by disrupting folate-dependent metabolic processes essential for cell replication. Pemetrexed disodium heptahydrate has the chemical name L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d] pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. It is a white to almost-white solid with a molecular formula of C20H19N5Na2O6•7H2O and a molecular weight of 597.49.
The structural formula is as follows: