Accolate is the brand name for the generic drug named zafirlukast. This drug is used to prevent asthma attacks, not to stop asthma attacks. Therefore it is important that your doctor be notified immediately if you experience tiredness or fatigue, nausea, eyes or skin turn yellow, flu-like feelings, or abdominal pain in the area of the liver (upper left). These symptoms can indicate that a problem with the liver is developing.
Accolate needs to be taken for several weeks before the full effects can be achieved. It is important to keep asthma medicine available at all times. Accolate needs to be taken regularly to achieve optimal results. If you need more than your typical dosage or require more than the maximum 24 hour dosage, then you should contact your physician. The increase dosage could be an indicator of a severe asthma attack. Alcohol and accolade can affect the liver. Discuss with your doctor your alcohol consumption while using Accolate.
Accolate is a leukotriene inhibitor, which means it blocks the agents that constrict and irritate airways; and it blocks build-up of fluid in the lungs. Fluid build-up, airway constriction and airway irritation are symptoms which occur during an asthma attack. It is important to remember that Accolate cannot treat an asthma attack as it occurs; it is used to prevent asthma attacks. Accolate can be used for other conditions not detailed in this description.
Before taking Accolate, you should discuss with your healthcare practitioner if you have liver disease or drink alcohol. The drug can affect the liver, so if you have liver disease or drink alcohol, you may not be able to take Accolate, require a different dose or require close surveillance while taking Accolate. If you are taking the blood thinner warfarin, the same conditions may apply: you may not be able to take Accolate, require a different dose or require close surveillance while taking Accolate. The US FDA categorizes drugs based on safety for pregnant women. Accolate is categorized as B. This indicates that this drug is not EXPECTED to cause harm to an unborn child, but you should discuss all risk factors with your doctor before taking this medication if you are expecting. Accolate can pass through breast milk to an infant. Do not take Accolate if you are nursing; discuss the safety with the pediatrician and your physician first. Patients under 5 are not approved to use Accolate. Patients over sixty are more likely to have side effects and may require a lower amount of the medicine.
Your doctor will indicate how to administer Accolate. If you have any questions, about taking this drug, call your physician, nurse practitioner or pharmacist. Do not stop taking this drug without first notifying your physician. The effects of this drug will not be apparent until it has been administered for a few weeks.
If you miss a dose of this drug, take the correct dose as soon as you realize that you’ve missed a dose. If it is almost time for the next dose, do not double up your dose! Simply take the next dose due in your medication schedule. If you believe you have overdosed on the medication go to the nearest emergency room or contact your physician.
To optimize this medication, avoid known allergens that can aggravate your allergy symptoms. Clean dusty environments which may also have pet fur.
A common allergic reaction to any drug has these symptoms: difficulty breathing, swelling or closing of throat, hives, swelling of face or tongue, rash, open sores, bruising or worsening respiratory symptoms. These symptoms indicate that you may be allergic to Accolate. Get medical attention immediately. Other less, serious side effect should be discussed with your doctor. These side effects are dizziness, headaches, and gastrointestinal upset, such as nausea, vomiting, or diarrhea.
Drugs that can affect Accolate are aspirin, erythromycin, warfarin or theyphyline. Make sure your doctor knows if you are taking any of these drugs.
As always, if you need more information, contact your physician or pharmacist regarding this medication.
Accolate is a synthetic, selective peptide leukotriene receptor antagonist (LTRA), with the chemical name 4-(5-cyclopentyloxy -carbonylamino-1-methyl -indol-3-ylmethyl)-3-methoxy-N-o- tolylsulfonylbenzamide. The molecular weight of zafirlukast is 575.7. Zafirlukast, a fine white to pale yellow amorphous powder, is practically insoluble in water. It is slightly soluble in methanol and freely soluble in tetrahydrofuran, dimethyl-sulfoxide, and acetone. ACCOLATE is supplied as 10 and 20 mg tablets for oral administration.
Accolate has the following structural formula: